Technical References

The Cerex MAX sensor is an optical density type sensor appropriate for use in the monitoring and control of a number of fermentations (ref. 2, 4, 6,7).  It has been successfully used in high cell density commercial bakers’ yeast fermentations over extended numbers of fed batch cycles (ref. 1).  The MAX sensor has also been used in research applications for the monitoring of high temperature bacterial fermentations at lower optical densities (ref. 3) as well as for E. coli fermentations (ref. 5,8,9).


  1. Hatch, R. T., Veilleux, B. G. 1995. Monitoring of Saccharomyces cerevisiae in Commercial Bakers’ Yeast Fermentation. Biotechnol. Bioeng. 46: 371-374.
  2. Hatch, R.T. 1982. Computer applications for analysis and control of fermentations. pp. 291-311 In: G.T. Tsao (ed.), Annual reports of fermentation processes, Vol. 5 Academic Press, New York.
  3. Krahe, M., Antranikian, G., and Karkl, H. 1996. Fermentation of extremophilic microorganisms. FEMS Microbiol. Rev. 18: 271-285.
  4. Phillips, J. 1988 . Novel sensors for the monitoring of fermentation processes. pp.15-34 In: Computer control of fermentation processes. CRC Press, Boca Raton, FL.
  5. Shiloach, J., Bahar, S., Miller, B. 1994. On-line monitoring of bacterial mass using an in-situ steam sterilizable sensor. pp. 244-250 In: R.M. Kelly, K.D. Wittrup, and F. Karkare (eds.), Biochemical engineering VIII, Vol. 745. New York Academy of Sciences, New York.
  6. Yamane, T., Hibino, W., Ishihara, K., Kadotani, Y., Kominami, M. 1992. Fed-batch culture automated by uses of continuously measured cell concentration and culture volume. Biotechnol. Bioeng. 39: 550-555.
  7. Yamane, T. 1993. Application of an on-line turbidimeter for the automation of fed-batch cultures. Biotechnol. Prog. 9: 81-85.
  8. On-Line Monitoring of Bacterial Mass Using In-situ Stream Sterilizable Sensor
  9. Performance of a Commercially Available Biomass Senser for On-Line Monitoring of High Density Escherichia coli

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